221. Dr. Marta DiForte | Cannabis and Schizophrenia - genetics or enviornment?

Episode 220 March 17, 2025 01:09:37
221. Dr. Marta DiForte | Cannabis and Schizophrenia - genetics or enviornment?
High Truths on Drugs and Addiction
221. Dr. Marta DiForte | Cannabis and Schizophrenia - genetics or enviornment?

Mar 17 2025 | 01:09:37

/

Show Notes

The Impact of Schizophrenia Genetic Load and Heavy Cannabis Use on the Risk of Psychotic Disorder in the EU-GEI case control and UK Biobank studies.  This article published in Psychology Magazine Apri 2024 studied 114,698 European patients to determine if genetics was associated with cannabis associated psychotic disorder. Regular users of high potency THC (over 10%) had the highest odds of psychotic disorder independent of schizophrenia genetics. Dr. Marta DiForte explains this research.

Dr Marta Di Forti is a Clinical Reader in Psychosis Research at the Dept of Social, Developmental and Genetic Research, Institute of Psychiatry, and Honorary Consultant Adult Psychiatrist, Lambeth EI Community team, South London and Maudsley NHS foundation Trust. She leads the first Cannabis Clinic for patients with Psychotic disorders in UK. She was recently awarded the Royal College of Psychiatrist Researcher of the year prize.  In 2020 she was granted a MRC Senior Research Fellowship to expand her research in the role of cannabis use in psychosis and its underlying biology. With her team she showed for the first time that use of high potency types of cannabis e.g. "skunk" carries a higher risk of psychosis than use of traditional types and that it affects rates of Psychotic disorders across Europe. Though it still remains unclear who are those cannabis use most at risk. Her future work aims to investigate the interaction between cannabis use and genes predisposing to schizophrenia, and how cannabis changes the epigenome.

Other Episodes

Episode 190

August 12, 2024 00:57:59
Episode Cover

Episode #190 High Truths on Drugs and Addiction with Dr. Gary Tsai on Addiction in LA

LA County California Gary Tsai, M.D. is a physician executive who is the Director of the Substance Abuse Prevention and Control, a division of...

Listen

Episode 247

September 15, 2025 01:06:21
Episode Cover

247. Rabbi Eliyahu Shusterman | Faith and Recovery

Faith is an important tool in recovery. Not everyone has is, but if you do, you should tap into this magical source. Globally, about...

Listen

Episode 118

March 27, 2023 00:49:13
Episode Cover

Episode #118 High Truths on Drugs and Addiction with Dr. James Mahoney and Brain Surgery for Addiction

Brain Surgery for Addiction? Listen to Dr. James Mahoney discuss his research on using deep brain stimulation with implanted electrodes that target the pleasure...

Listen